Marian Wielosz Selected Research

Felbamate (Felbatol)

1/2011	Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice.
7/2007	Enhanced glutamatergic transmission reduces the anticonvulsant potential of lamotrigine but not of felbamate against tonic-clonic seizures.
7/2006	Enhancement of brain kynurenic acid production by anticonvulsants--novel mechanism of antiepileptic activity?
7/2003	Influence of some convulsant agents on the protective activity of a novel antiepileptic drug, felbamate, against maximal electroshock in mice.

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Marian Wielosz Research Topics

Disease

13	Seizures (Absence Seizure) 01/2011 - 01/2002
4	Epilepsy (Aura) 07/2006 - 08/2004
2	Hypoxia (Hypoxemia) 05/2003 - 07/2002
1	Ataxia (Dyssynergia) 01/2011
1	Tonic-Clonic Epilepsy (Epilepsy, Tonic Clonic) 05/2009
1	Hyperglycemia 05/2007
1	Atherosclerosis 05/2007
1	Status Asthmaticus 07/2005
1	Ischemia 05/2003
1	Carbon Tetrachloride Poisoning 01/2003
1	Memory Disorders (Memory Loss) 08/2002
1	Hypoglycemia (Reactive Hypoglycemia) 07/2002

Drug/Important Bio-Agent (IBA)

8	Anticonvulsants (Antiepileptic Drugs)IBA 01/2011 - 01/2002
5	Kynurenic Acid (Kynurenate)IBA 05/2007 - 07/2002
4	Felbamate (Felbatol)FDA Link 01/2011 - 07/2003
3	Bupropion (Wellbutrin)FDA LinkGeneric 01/2011 - 09/2004
3	Lamotrigine (Lamictal)FDA LinkGeneric 01/2011 - 07/2006
3	Pentylenetetrazole (Metrazol)IBA 05/2009 - 05/2003
3	Glutamic Acid (Glutamate)FDA Link 05/2007 - 07/2002
3	Phenobarbital (Luminal)FDA Link 07/2006 - 01/2005
3	Clonazepam (Rivotril)FDA LinkGeneric 01/2006 - 05/2003
3	Valproic Acid (Depakote)FDA LinkGeneric 01/2006 - 05/2003
2	Topiramate (Topamax)FDA LinkGeneric 01/2011 - 05/2005
2	N-Methylaspartate (NMDA)IBA 07/2007 - 05/2003
2	3-nitropropionic acidIBA 05/2007 - 01/2005
2	Aminooxyacetic AcidIBA 05/2007 - 07/2002
2	Glutamate Receptors (Glutamate Receptor)IBA 05/2007 - 07/2002
2	Histamine Receptors (Histamine Receptor)IBA 01/2006 - 07/2005
2	Cimetidine (Biomet)FDA LinkGeneric 01/2006 - 07/2005
2	Aminophylline (Carine)FDA LinkGeneric 07/2005 - 01/2005
2	Transaminases (Aminotransferases)IBA 05/2003 - 07/2002
2	EnzymesIBA 05/2003 - 01/2003
2	Molsidomine (SIN 10)IBA 08/2002 - 02/2002
1	Kainic Acid (Kainate)IBA 07/2007
1	HomocysteineIBA 05/2007
1	Cysteine (L-Cysteine)FDA Link 05/2007
1	Carbamazepine (Tegretol)FDA LinkGeneric 07/2006
1	Phenytoin (Dilantin)FDA LinkGeneric 07/2006
1	AstemizoleIBA 07/2005
1	Famotidine (Pepcid)FDA LinkGeneric 07/2005
1	Antazoline (Antazoline Phosphate)FDA Link 07/2005
1	ConvulsantsIBA 05/2005
1	Antidepressive Agents (Antidepressants)IBA 03/2005
1	Nicotine FDA Link 03/2005
1	Adenosine A1 ReceptorIBA 01/2005
1	Diazepam (Valium)FDA LinkGeneric 01/2005
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2005
1	Anti-Allergic Agents (Antiallergic Agents)IBA 08/2004
1	Histamine H1 Receptors (Histamine H1 Receptor)IBA 08/2004
1	PicrotoxinIBA 07/2003
1	StrychnineIBA 07/2003
1	BicucullineIBA 07/2003
1	Ethosuximide (Zarontin)FDA LinkGeneric 05/2003
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2003
1	KynurenineIBA 05/2003
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2003
1	Excitatory Amino Acid AntagonistsIBA 05/2003
1	Vigabatrin FDA Link 05/2003
1	AntioxidantsIBA 01/2003
1	GYKI 52466IBA 08/2002
1	Riluzole FDA LinkGeneric 08/2002
1	Dizocilpine Maleate (Dizocilpine)IBA 08/2002
1	Aspartic Acid (Aspartate)FDA Link 07/2002
1	beta Adrenergic ReceptorsIBA 01/2002

Therapy/Procedure

1	Subcutaneous Injections 05/2003